Integrated device for faeces sampling and occult blood detection

ABSTRACT

Disclosed is an integrated device for faeces sampling and occult blood detection, which has functions of quantitative collection, dissolution, filtration, detection with immune test strips of the faecal sample, and is convenient to carry and operate, and the device does not leak any liquid during storage, transportation and detection. The device can accurately collect a constant sample with no pollution and leakage, and can quickly determine results of occult blood without the aid of other items. The device can detect faecal occult blood at any time and at any place, can help to overcome the problem of low rate of inspection due to the inconvenience of faeces submission and inspection, further promote the detection of faecal occult blood, and can improve the early diagnosis and screening rate of colorectal cancer of the population.

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. application Ser. No.16/484,731, filed Aug. 8, 2019, now allowed, which is a U.S. NationalPhase application, filed under 35 U.S.C. § 371, of InternationalApplication No. PCT/CN2017/102799, filed Sep. 21, 2017, which claims thebenefit of, and priority to, Chinese Patent Application No.201710078782.4, filed Feb. 14, 2017. Each of these documents isincorporated by reference herein in its entirety for all purposes.

BACKGROUND Technical Field

The present invention belongs to medical equipment, and relates to anassistant in vitro diagnosis utensil, and in particular, to anintegrated device for faeces sampling and occult blood detection.

Related Art

Faeces occult blood detection is one of important technologies for earlydiagnosis of colorectal cancer and screening of populations, byperforming colonoscopy on patients with faeces occult blood beingpositive, the tumor detection rate may be increased by 4-6 times, andcolonoscopy is an optimal method for screening high-risk populationswith colorectal tumor. That the colorectal cancer morbidity andmortality rates are obviously reduced by detecting faeces occult bloodevery year has already been verified by multiple large-scale queueresearch institutions. Faeces occult blood detection has beenrecommended as a leading screening technology for colorectal cancer ofthe populations by multiple authorities including American CancerSociety, colorectal cancer early diagnosis and early treatment projectsof the Ministry of Health of China, Chinese Society of Gastroenterologyof Chinese Medical Association and the like.

In conventional faeces occult blood detection, an examinee needs toreserve faeces for submission and inspection, and professional staff ofa hospital are needed for detection. However, because the requirementsfor faeces collection and storage and transportation of the sample forsubmission and inspection are relatively high, a person going to thehospital for physical examination generally neglects submission andinspection of faeces or does not submit because of having no awarenessof defecation. Therefore, in actual population screening and physicalexamination, faeces sampling and submission and inspection rates arerelatively low. In a colorectal cancer screening test performed inXiacheng District in Hangzhou, Xuhui District in Shanghai and NanggangDistrict in Harbin, the faeces submission and inspection rate of thecommunity residents does not reach 40%. While actually, an operationmethod of detecting the faeces occult blood with a colloidal gold teststrip is very simple, similar to an early pregnancy test strip, and acommunity resident can detect and judge at home by himself.

However, faeces detection is obviously different from urine detection.Firstly, faeces is easier to pollute than urine, and no one is willingto directly view or contact the faeces. Secondarily, faeces is solid,and may be subjected to immune test strip detection only after beingsufficiently dissolved in liquid first. Then, control on the faecessampling amount is more difficult than urine. Finally, in detectionoperation, it must ensure that faecal liquid does not leak, or thefaecal liquid is not suitable for household or non-specialized homedetection. A utensil for self-detection of faeces occult blood is stillabsent on the market currently, some factories of faeces occult bloodreagent adopting an immunogold method design respective faeces samplingutensils, but the faeces sampling utensils do not have a sampling amountcontrol device, and none of them includes a detector, and in alldetection, the faecal liquid must be open. Currently, faeces occultblood is performed by being limited in professional medicalinstitutions, and in detection, the professional staff generally put thefaeces into a container with a buffer solution first to dissolve, thenpour the faeces liquid in the container into a small cup or a smallhole, and then insert a liquid-absorbing test strip into the small cupor the small hole for detection. In detection, the faeces liquid isopen, the professional staff need to directly view the faeces for manytimes, in operation, the small cup and the small hole turn over easilyand leak liquid, then the professional staff need to operate by wearinggloves, and the detection utensils are dispersed and do not form acomplete set, and thus the detection utensils are inconvenient to carryand transport, these disadvantages cause the situation that the currentfaeces occult blood cannot be independently examined by anon-specialized person.

Faeces occult blood is early earning for abnormity of the alimentarycanal, and when the bleeding amount of the alimentary canal is less, noabnormal change may occur to the outer shape of the faeces, and itcannot be recognized by naked eyes. Therefore, faeces occult bloodinspection needs to be performed on a patient suspected to have chronicbleeding in the alimentary canal, which has significant meaning on earlyscreening of malignant tumors (such as stomach cancer, colorectalcancer, polyp and adenoma) of the alimentary canal. In conventionalimmune detection method, i.e. hemoglobin detection method, the patientneeds to go to a professional hospital or physical examinationorganization for inspection by using a sampling tube or a kit. Thepatient reserves the faeces sample, the medical inspection personnelsamples with the sampling tube, mixes quantitative faeces with astabilizing solution, and drips the mixed solution into a faeces occultblood kit, and according to the colloidal gold immunochromatographyprinciple, the mixed solution is siphoned by a test strip in the kit andspreads, then a color zone appears, and whether the faeces occult bloodis negative or positive is judged by comparison of the color of thecolor zone with a standard color card.

SUMMARY

The present invention aims to provide an integrated device for faecessampling and occult blood detection, including a lid, a main bodycontainer sealed tube, a stop block, a piston, a test strip slot seat, asealing sheet, a base, and a faeces sampling stick; the lid is providedwith an inner ring and a C-shaped outer ring, the diameter of the innerring is tightly adapted to the inner diameter of a round tube chamber, asmooth tube wall is adopted to tightly fit to the round tube chamberwhich can be sealed so as to ensure that no matter in the containerleaks, the diameter of the C-shaped outer ring is adapted to the outerdiameter of the round tube chamber, the C-shaped outer ring is sleevedover the round tube chamber, a clearance between the inner ring and theC-shaped outer ring is adapted to the tube wall of the round tubechamber, the faeces sampling stick is fixed at the center of the innerring, the free end of the faeces sampling stick is provided with athreaded structure to be used for staining faeces, the faeces samplingstick is tightly adapted to a round hole inside a separation layer 15,the faeces sampling stick not only can scrape redundant faeces on thethreaded surface but also can form secondary sealing when passing so asto prevent inverted overflow of faeces liquid, a small hole is providedin the tube wall of the inner ring at the opening of the C-shaped outerring to be adapted to a bulge of the stop block, and when the bulge isinserted into the small hole, the stop block can be prevented fromsliding up and down, so as to play a role of fixing.

The main body container sealed tube is combined by a round tube chamberfor storing liquid and a test strip rectangular tube chamber, the top ofthe rectangular tube chamber is sealed, the the separation layer whichhas a funnel shape with a round hole in the center is provided in theround tube chamber, and the diameter of the hole is adapted to thediameter of the faeces sampling stick, so that the threaded structure ofthe faeces sampling stick passes to scrape residual faeces on thethreaded surface.

The size and shape of the stop block are adapted to the section of therectangular tube chamber, the bulge is provided on the inside wall ofthe stop block and adapted to a small hole of the lid, so as to realizedismounting and fixing of the stop block, and the stop block is locatedat the top of the rectangular tube chamber, so as to prevent the faecessampling stick from inserting in advance due to misoperation.

A test strip slot is provided at one side of the test strip slot seat,the test strip slot communicates with the base, so that glass fiber atthe bottom of the test strip may contact with the solution, the otherside of the test strip slot seat is provided with a piston slot with ahole in the center, piston supports are provided on the upper edge ofthe piston slot, so that the piston is supported without sliding downbefore acting, the outer shape of the test strip slot seat is adapted tothe main body container sealed tube, the test strip slot is insertedinto the rectangular tube chamber, and the piston slot is located in theround tube chamber.

The base is sleeved with the bottom of the test strip slot seat, asolution receiving slot is provided in the base, a groove is locatedbelow the test strip slot, a slope is provided between the receivingslot and the groove, a quantitative solution entering the receiving slotvia the piston slot is guided to flow into the groove via the slope, sothat the glass fiber at the bottom of the test strip just contacts withthe solution in the groove, and the mixed solution starts to spreadunder the siphon action of the glass fiber of the test strip, and then acolor zone appears.

The sealing sheet is clung to the back of the piston slot, and thepiston is placed on the piston supports, at the moment, no solutionexists in the base, and after the piston is pressed down, the piston rodwith a sharp end can pierce the sealing sheet, so that the solutionenters the receiving slot of the base quantitatively.

The diameter of one end, close to the lid, of the faeces sampling stickis greater than that of the free end, so as to be matched with the roundhole inside the separation layer more tightly.

The volume of the piston slot is set according to a quantitativerequirement.

A drying agent is put into the rectangular tube chamber, so as to play arole of protecting the humidity-sensitive colloidal gold test strip.

The main body container sealed tube, the test strip slot seat and thebase are assembled together, and hermetical welding of the three isachieved by adopting an ultrasonic welding technology.

The using method of the device of the present invention is as follow:

1. The lid 1 is taken down, and faeces is collected with the free end ofthe faeces sampling stick, so that the faeces stains the threaded partof the faeces sampling stick.

2. The faces sampling stick 8 is inserted back into the round tubechamber 13, and the utensil is shaken, so that the faeces issufficiently dissolved in the solution.

3. The stop block 3 is dismounted, the lid 1 is pressed to the bottom,at the moment, the faeces sampling stick pushes down the piston 4, sothat the sharp end of the piston rod 11 pierces the sealing sheet 6, andthe quantitative mixed solution in the piston slot 12 enters thereceiving slot 21 of the base 7.

4. The mixed solution is allowed to flow into the groove 22 of the base7 via the slope, wherein the bottom of the groove 22 just contacts withthe glass fiber at the bottom of the test strip, the mixed solutionstarts to spread under the siphon action of the test strip, and then acolor zone appears.

5. After 10 minutes, the color of the quality control line of anobservation window of the test strip and the color a detection linestrip are checked, and comparison is conducted with a color card, aresult is determined.

Principle of the Present Invention:

The lid 1 with the faeces sampling stick is used for faeces sampling,and the tail end of the faeces sampling stick has a thread, so as toperform quantitative sampling. The lid is inserted into the tube body, athe separation layer which has a funnel shape is provided in the tubebody to divide the tube body into an upper tube chamber and a lower tubechamber, a hole with proper size is provided inside the separation layerand just allows the faeces sampling stick with thread to pass, so as toplay the role of scraping redundant faeces, the faeces sampling stickreaches the lower tube chamber, the lower tube chamber is filled withthe stabilizing solution in advance, and the faeces on the thread of thefaeces sampling stick is dissolved in the stabilizing solution to form asample mixed solution. The stop block is assembled on the lid, earlyspreading of the test strip caused by misoperation is avoided in thesampling and faeces and stabilizing solution shaking and mixingprocesses, after sampling is completed, the stop block is dismounted,the lid may be pressed down completely, the piston is pushed to movedownwards, the piston is mounted in the test strip slot and is downwardpushed into a piston slot 12 of a sealed space formed by the round tubechamber at the lower part of the test strip slot seat, the volume of thesealed space is the transferred quantitative volume of the sample mixedsolution, pushing downward is continued, the piston rod at the lowerpart of the piston ruptures the sealing sheet sealing the small roundhole at the lower part of the test strip slot, and the sample mixedsolution with quantitative volume is pressed to the base by the smallhole 18 in the piston slot 12. The base has a round tube chamberreceiving slot 21 for receiving the pressed-in sample mixed solution,the receiving slot 21 has a slope for guiding the sample mixed solutioninto the groove 22 of the base. The bottom of the test strip stuck bythe test strip slot contacts with the sample mixed solution in thegroove 22, the mixed solution starts to spread under the siphon actionof the glass fiber of the test strip, a color zone appears, and thencomparison with the color card may be performed, so as to determine theresult. A tablet drying agent may be provided at the clearance of therectangular tube chamber 14 of the test strip, so as to play the role ofprotecting the humidity-sensitive colloidal gold test strip, the tubebody, the test strip slot and the base are assembled together, andhermetical welding of the three is achieved by adopting an ultrasonicwelding technology.

The utensil is simple in structure, low in production cost, andconvenient in operation, the faecal liquid does not need to be placed inthe open, the test can be completed one time after faeces sampling, andthe utensil is clean and safe. By implementation of the presentinvention, an ordinary person can accurately and cleanly complete faecesoccult blood test according to brief introduction without anyprofessional training, and determine the detection result; a constantamount of faeces may be accurately collected, without causing anypollution, or causing faeces liquid leakage, and the occult blood resultmay be rapidly tested without the aid of other items; a common adult canperform faeces occult detection at any time and at any place; andtherefore, the present invention can help to overcome the problem of lowrate of inspection due to the inconvenience of faeces submission andinspection, further promote the detection of faeces occult blood, andcan improve the early diagnosis and screening rate of colorectal cancerof the population.

The present invention overcomes disadvantages of the prior art, and wellsolves the foregoing problems, and the invented utensil integrates thefunctions of quantitative collection, dissolution, filtration, detectionwith immune test strips of the faeces sample, is convenient to carry andoperate, the test can be conducted without directly viewing the faecesafter sampling, and the device does not leak any liquid during storage,transportation and detection. A common adult can perform feces occultblood self detection at any time and at any place. According to thepresent invention, the sampling tube and the test strip are combined inone kit, and the liquid storage tube chamber and the test strip tubechamber are sealed and independent relatively. A patient can detect athome, and can complete sampling, detection and determination at homeaccording to instructions. The operation is convenient and quick. Thesample preservation freshness and the detection result accuracy areincreased.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a structure schematic diagram of the present invention.

FIG. 2 is a structure schematic diagram of a test strip slot part.

FIG. 3 is a structure schematic diagram of a tube body part.

FIG. 4 is a structure schematic diagram of a lid part.

FIG. 5 is a structure schematic diagram of a stop block part.

FIG. 6 is a structure schematic diagram of a bottom part.

FIG. 7 is a structure schematic diagram of a piston part.

FIG. 8 is a state diagram before use of the device of the presentinvention.

DETAILED DESCRIPTION

Further description will be made to the present invention in combinationwith accompanying drawings and embodiments.

Embodiment 1

Referring to FIG. 1 to FIG. 7, the integrated device for faeces samplingand occult blood detection includes a lid 1, a main body containersealed tube 2, a stop block 3, a piston 4, a test strip slot seat 5, asealing sheet 6, a base 7, and a faeces sampling stick.

The lid 1 is provided with an inner ring 16 and a C-shaped outer ring17. The diameter of the inner ring 16 is tightly adapted to the innerdiameter of a round tube chamber 13. A smooth tube wall is adopted totightly fit to the round tube chamber 13 which can be sealed so as toensure that no matter in the container leaks. The diameter of theC-shaped outer ring 17 is adapted to the outer diameter of the roundtube chamber 13. The C-shaped outer ring 17 is sleeved over the roundtube chamber. A clearance between the inner ring 16 and the C-shapedouter ring 17 is adapted to the tube wall of the round tube chamber 13.The faeces sampling stick 8 is fixed at the center of the inner ring 16.The free end of the faeces sampling stick 8 is provided with a threadedstructure 19 to be used for staining faeces. The faeces sampling stick 8is tightly adapted to a round hole inside a separation layer 15. Thefaeces sampling stick 8 not only can scrape redundant faeces on thethreaded surface but also can form secondary sealing when passing so asto prevent inverted overflow of faeces liquid. The inner ring 16 has asmall hole 18 in the tube wall at the opening of the C-shaped outer ring17 to be adapted to a bulge 20 of the stop block 3. When the bulge 20 isinserted into the small hole 18, the stop block 3 can be prevented fromsliding up and down, so as to play a role of fixing.

The main body container sealed tube 2 is combined by a round tubechamber 13 for storing liquid and a test strip rectangular tube chamber14. The top of the rectangular tube chamber 14 is sealed. The theseparation layer which has a funnel shape 15 with a round hole in thecenter is provided in the round tube chamber 13. The diameter of thehole is adapted to the diameter of the faeces sampling stick 8, so thatthe threaded structure 19 of the faeces sampling stick 8 passes toscrape residual faeces on the threaded surface.

The size and shape of the stop block 3 are adapted to the section of therectangular tube chamber 14. The bulge 20 is provided on the inside walland adapted to a small hole 18 of the lid 1, so as to realizedismounting and fixing of the stop block 3. The stop block 3 is locatedat the top of the rectangular tube chamber 14, so as to prevent thefaeces sampling stick 8 from inserting in advance due to misoperation.

A test strip slot 9 is provided at one side of the test strip slot seat5. The test strip slot 9 communicates with the base 7, so that glassfiber at the bottom of the test strip may contact with the solution. Theother side of the test strip slot seat 5 is a piston slot 12 with a holein the center. Two piston supports 10 are provided on the upper edge ofthe piston slot 12, so that the piston 4 is supported without slidingdown before acting. The outer shape of the test strip slot seat 5 isadapted to the main body container sealed tube 2. The test strip slot 9is inserted into the rectangular tube chamber 14. The piston slot 12 islocated in the round tube chamber 13.

The base 7 is sleeved with the bottom of the test strip slot seat 5. Asolution receiving slot 21 is provided in one side of the base 7. Agroove 22 is located below the test strip slot 9 at the other side. Aslope is provided between the receiving slot 21 and the groove 22. Thequantitative solution entering the receiving slot 21 via the piston slot12 is guided to flow into the groove 22 via the slope, so that the glassfiber at the bottom of the test strip just contacts with the solution inthe groove 22. The mixed solution starts to spread under the siphonaction of the glass fiber of the test strip, and then a color zoneappears.

The sealing sheet 6 is clung to the back of the piston slot 12 to sealthe small hole in the piston slot 12, and the piston 4 is placed on thepiston supports 10. At the moment, no solution exists in the base 7, andafter the piston 4 is pressed down, the piston rod 11 with a sharp endcan pierce the sealing sheet 6, so that the solution enters thereceiving slot 21 of the base 7 quantitatively.

The diameter of one end, close to the lid, of the faeces sampling stick8 is greater than that of the free end (the end with the threadedstructure), so as to be matched with the round hole inside theseparation layer 15 more tightly.

The volume of the piston slot 12 is set according to a quantitativerequirement.

The main body container sealed tube 2, the test strip slot seat 5 andthe base 7 are assembled together, and hermetical welding of the threeis achieved by adopting an ultrasonic welding technology.

The Mounting Sequence:

1. The bulge 20 of the stop block 3 is inserted into the small hole 18of the lid, the faeces sampling stick 8 is inserted into the round tubechamber 13 of the main body container sealed tube 2 already filled withthe stabilizing solution, at the moment, the stop block 3 is located atthe top of the rectangular tube chamber 14, the inner ring of the lidand the opening of the round tube chamber of the main body containersealed tube 2 are tightly sealed, and the faeces sampling stick 8 andthe round hole inside the separation layer 15 are sealed, so that theliquid does not leak during storage and transportation.

2. The piston is placed on the piston supports 10, and the sealing sheet6 is stuck at the back of the piston slot 12, so as to seal the pistonslot 12.

3. The test strip is inserted into the test strip slot 9, the base 7 iscombined with the test strip slot seat 5 and is sealed by ultrasonicwelding, a drying agent 23 (referring to FIG. 8) is put into theclearance in the rectangular tube chamber 14, so as to play a role ofprotecting the humidity-sensitive colloidal gold test strip, and thelower side of the container sealed tube 2 is sleeved with the test stripslot seat 5, so as to form a sealed device.

Embodiment 2 Using Method of the Device

1. The lid 1 is taken down, and faeces is collected with the free end ofthe faeces sampling stick, so that the faeces stains the threaded partof the faeces sampling stick.

2. The faces sampling stick 8 is inserted back into the round tubechamber 13, and the utensil is shaken, so that the faeces issufficiently dissolved in the solution.

3. The stop block 3 is dismounted, the lid 1 is pressed to the bottom,at the moment, the faeces sampling stick pushes down the piston 4, sothat the sharp end of the piston rod 11 pierces the sealing sheet 6, andthe quantitative mixed solution in the piston slot 12 enters thereceiving slot 21 of the base 7.

4. The mixed solution is allowed to flow into the groove 22 of the base7 via the slope, wherein the bottom of the groove 22 just contacts withthe glass fiber at the bottom of the test strip, the mixed solutionstarts to spread under the siphon action of the test strip, and then acolor zone appears.

5. After 10 minutes, the color of the quality control line of anobservation window of the test strip and the color of a detection linestrip are checked, comparison is conducted with a color card, and aresult is determined.

Embodiment 3

Compared with the structure of the prior art, the present invention hasthe following advantages:

1. The product production efficiency is increased, and the operationprocedure is reduced: ultrasonic welding is adopted for the base, only afew seconds is needed for welding one base, while previous products needto be smeared with glue, and 8 hours or more are needed for completelybonding the products.

2. The product quality is improved: ultrasonic welding ensures that thebase is sealed, so as to reduce or completely eradicate the risk ofliquid leakage. The previous products are smeared with glue, and theglue causes influence to the functions of the buffer solution andspreading of the test strip, and then product sensitivity is reduced orfalse positive is caused.

3. The use convenience is increased: the test is completed by justunplugging the lid, sampling, inserting the lid back, shaking,unplugging the stop block, pressing down the lid, and determining thecolor zone appearing by spreading in set time. For previous products,the test is completed by unplugging the lid, sampling, inserting the lidback, shaking, tearing down a safety paster, pressing down the lid,unplugging the lid to the home position, pinching the tube body byexerting strength, and waiting for the outer shape of the color zone.The time for the outer shape of the color zone is uncontrollable, thestrength for different operators to pinch the tube body isuncontrollable, and then the determination result is great indifference.

4. The sample liquid needed for spreading can be quantified, and foreach product, the volume of the liquid pushed to transfer by the pistonis the same, without being affected by different operators. For theprevious products, different persons pinch the tube body, and becausethe pinch strength is different, the transferred liquid amount isuncontrollable.

What is claimed is:
 1. An integrated device for faeces sampling andoccult blood detection, comprising a lid (1), a main body containersealed tube (2), a stop block (3), a piston (4), a test strip slot seat(5), a sealing sheet (6), a base (7), and a faeces sampling stick (8),the lid (1) being provided with an inner ring (16) and a C-shaped outerring (17), the diameter of the inner ring (16) being adapted to theinner diameter of a round tube chamber (13), the diameter of theC-shaped outer ring (17) being adapted to the outer diameter of theround tube chamber (13), a clearance between the inner ring (16) and theC-shaped outer ring (17) being adapted to the tube wall of the roundtube chamber (13), the faeces sampling stick (8) being fixed at thecenter of the inner ring (16), the free end of the faeces sampling stick(8) being provided with a threaded structure (19), the faeces samplingstick (8) being tightly adapted to a round hole inside a separationlayer (15), a small hole (18) being provided in the tube wall of theinner ring (16) at the opening of the C-shaped outer ring (17) to beadapted to a bulge (20) of the stop block (3), the main body containersealed tube (2) being combined by the round tube chamber (13) forstoring liquid and a rectangular tube chamber (14), the top of therectangular tube chamber (14) being sealed, the separation layer (15)which has a funnel shape with a round hole in the center being providedin the round tube chamber (13), the shape of the stop block (3) beingadapted to the section of the top of the rectangular tube chamber (14),the bulge (20) being provided on the inside wall of the stop block (3)and adapted to a small hole (18) of the lid (1), the stop block (3)being located at the top of the rectangular tube chamber (14), a teststrip slot (9) being provided at one side of the test strip slot seat(5), the other side of the test strip slot seat (5) being provided witha piston slot (12) with a hole in the center, two piston supports (10)being provided on the upper edge of a piston slot (12), the outer shapeof the test strip slot seat (5) being adapted to the main body containersealed tube (2), the base (7) being sleeved with the bottom of the teststrip slot seat (5), a solution receiving slot (21) being provided inone side of the base (7), the other side of the base (7) being providedwith a groove (22) in a part located below the test strip slot (9), aslope being provided between the receiving slot (21) and the groove(22), and the sealing sheet (6) being clung to the back of the pistonslot (12), and the piston (4) being placed on the piston supports (10).2. The integrated device for faeces sampling and occult blood detectionaccording to claim 1, wherein the diameter of the round hole inside theseparation layer (15) which has a funnel shape is adapted to thediameter of the faeces sampling stick (8).
 3. The integrated device forfaeces sampling and occult blood detection according to claim 1 or 2,wherein the bulge (20) provided on the inside wall of the stop block (3)is adapted to the small hole (18) of the lid (1), so as to realizedismounting and fixing of the stop block (3).
 4. The integrated devicefor faeces sampling and occult blood detection according to claim 1 or2, wherein the test strip slot (9) communicates with the base (7). 5.The integrated device for faeces sampling and occult blood detectionaccording to claim 1 or 2, wherein the volume of the piston slot (12) isset according to a quantitative requirement.
 6. The integrated devicefor faeces sampling and occult blood detection according to claim 1 or2, wherein the test strip slot (9) is inserted into the rectangular tubechamber (14), and the piston slot (12) is located in the round tubechamber (13).
 7. The integrated device for faeces sampling and occultblood detection according to any one of claims 1-6, wherein the diameterof the end, close to the lid, of the faeces sampling stick (8) is largerthan that of the free end, and the faeces sampling stick (8) is tightlyadapted to the round hole inside the separation layer (15).
 8. Theintegrated device for faeces sampling and occult blood detectionaccording to any one of claims 1-6, wherein the main body containersealed tube (2), the test strip slot seat (5) and the base (7) arehermetically welded and assembled together by using an ultrasonicwelding technology.